U.K. Study to test mixed schedules of different Covid-19 vaccine

U.K. Study to test mixed schedules of different Covid-19 vaccine

U.K. Study to test mixed schedules of different Covid-19 vaccine

A U.K. study will look into the immune responses of children to mixed schedules of different Covid19 vaccines as officials try to determine the best approach to second doses in adolescents given a small risk of heart inflammation.

The trial will give the participants a first dose of the Pfizer-BioNTech vaccine. After eight weeks this will be followed by either a second full or just half a dose of Pfizer shot, a half dose of Moderna’s shot or a full dose of Novavax.

The trial is to recruit 360 volunteers, not large enough to directly assess the myocarditis risk of the different combinations, which, Matthew Snape of the Oxford Vaccine Group said was 1 in 15,000 after two doses of the Pfizer shot in young men.

Those aged 16-17 are eligible for shots since August, while children from 12-15 will be vaccinated from next week.